3 out of 10 Mumbai residents at high risk of heart attack; reveals Metropolis Healthcare Study

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~ 42,616 out of 1,35,054 samples analysed report dyslipidaemia; form the high risk group ~

Mumbai, September 29, 2016: In order to understand the intensity of the heart disease, Metropolis Healthcare conducted a comprehensive study on the population of Mumbai; ahead of World Heart Day falling on September 29th 2016. The study reveals 3 out of 10 Mumbai residents are at high risk of heart attack and a marginal population is at high risk of developing cardio vascular diseases. Among the 1,35,054 lipid profile samples that were collected for a period of five years (2011 – 2015); an alarming 33.14% of patients in the age group of 20-80 years have reported dyslipidaemia and also revealed:

· 33.14% samples reported high Total Cholesterol level

· 34.44% have high Triglyceride level

· 40% of the population have extremely low HDL levels, the good cholesterol and over 53% have less than desirable levels

· 30.68% have borderline high or high LDL levels

Dr. Deepak Sanghavi, Deputy Chief Of Lab, Metropolis Healthcare Ltd said, “The incidence and prevalence of cardiovascular disease has been steadily rising in India. The major factors attributed to this are changes in lifestyle, lack of exercise, consumption of non-nutritious food, increased stress level, smoking and irrational use of tobacco. Prolonged working hours, hectic commute and growing incidence of obesity along with sedentary lifestyle is also one of the reasons for Mumbai’s population to be more prone to heart ailments.”

High blood cholesterol and triglyceride –Usually there are no signs or symptoms. People with high blood cholesterol level have higher chances of developing cardiac risk. This results in development of plaques in the arteries.

Plaques are basically a substance made of fat, cholesterol which clogs the arteries depriving heart and brain from getting good amount of oxygen; this increases the chances of heart attack or stroke. The higher level of HDL (sometimes called good cholesterol) in the blood lowers the chances of developing heart disease.

The general perception is that heart disease is more prevalent in men, but women are equally at risk of developing cardiovascular disease. The main contributing factor is being unhealthy lifestyle, inappropriate diet and physical inactivity. Smoking and diabetes have also emerged as major factors responsible for causing cardiovascular diseases.

DATA SNAPSHOT

AGE WISE DATA

Total Cholesterol

Total

In %

Age Group

Desirable

Borderline High

High

Grand Total

Desirable

Borderline High

High

20 to 30

10369

2667

755

13791

75.19

19.34

5.47

30 to 40

17805

7417

2637

27859

63.91

26.62

9.47

40 to 50

17853

8010

3225

29088

61.38

27.54

11.09

50 to 60

17740

6836

2954

27530

64.44

24.83

10.73

60 to 70

14611

4113

1675

20399

71.63

20.16

8.21

70 to 80

7579

1650

677

9906

76.51

16.66

6.83

Grand Total

85957

30693

11923

128573

66.85

23.87

9.27

Triglycerides

Total

In %

Age Group

Desirable

Borderline High

High

Grand Total

Desirable

Borderline High

High

20 to 30

7137

1258

1147

9542

74.80

13.18

12.02

30 to 40

13913

3890

4414

22217

62.62

17.51

19.87

40 to 50

16770

5122

5194

27086

61.91

18.91

19.18

50 to 60

16751

5098

4522

26371

63.52

19.33

17.15

60 to 70

13429

3528

2661

19618

68.45

17.98

13.56

70 to 80

6954

1505

1021

9480

73.35

15.88

10.77

Grand Total

74954

20401

18959

114314

65.57

17.85

16.59

LDL

Total

In %

Age Group

Desirable

Near Optimal

Borderline High

High

Grand Total

Desirable

Near Optimal

Borderline High

High

20 to 30

3360

3015

1577

608

8560

39.25

35.22

18.42

7.10

30 to 40

5884

6982

4667

2074

19607

30.01

35.61

23.80

10.58

40 to 50

7708

7812

5887

2840

24247

31.79

32.22

24.28

11.71

50 to 60

9420

6774

5094

2689

23977

39.29

28.25

21.25

11.21

60 to 70

9000

4596

3009

1483

18088

49.76

25.41

16.64

8.20

70 to 80

5059

1987

1184

576

8806

57.45

22.56

13.45

6.54

Grand Total

40431

31166

21418

10270

103285

39.15

30.17

20.74

9.94

HDL

Total

In %

Row Labels

Desirable

Borderline High

Major Risk

Grand Total

Desirable

Borderline High

Major Risk

20 to 30

573

4734

3549

8856

6.47

53.46

40.07

30 to 40

957

10263

9412

20632

4.64

49.74

45.62

40 to 50

1417

13410

10593

25420

5.57

52.75

41.67

50 to 60

1635

13486

9746

24867

6.57

54.23

39.19

60 to 70

1442

10273

6852

18567

7.77

55.33

36.90

70 to 80

1015

5016

2972

9003

11.27

55.71

33.01

Grand Total

7039

57182

43124

107345

6.56

53.27

40.17

GENDER WISE DATA

Total Cholesterol

Total

In %

Gender

Desirable

Borderline High

High

Total

Desirable

Borderline High

High

F

39862

15188

6324

61374

64.95

24.75

10.3

M

51256

16353

6071

73680

69.57

22.19

8.24

Total

91118

31541

12395

135054

67.47

23.35

9.18

Triglycerides

Total

In %

Age Group

Desirable

Borderline High

High

Grand Total

Desirable

Borderline High

High

F

37687

8867

6856

53410

70.56

16.60

12.84

M

37264

11534

12102

60900

61.19

18.94

19.87

Grand Total

74951

20401

18958

114310

65.57

17.85

16.58

LDL

Total

In %

Age Group

Desirable

Near Optimal

Borderline High

High

Grand Total

Desirable

Near Optimal

Borderline High

High

F

18693

16056

10858

5466

51073

36.60

31.44

21.26

10.70

M

24570

16453

11126

5099

57248

42.92

28.74

19.43

8.91

Grand Total

43263

32509

21984

10565

108321

39.94

30.01

20.30

9.75

HDL

Total

In %

Row Labels

Desirable

Borderline High

Major Risk

Grand Total

Desirable

Borderline High

Major Risk

F

5992

33292

13205

52489

11.42

63.43

25.16

M

1673

26838

31808

60319

2.77

44.49

52.73

Grand Total

7665

60130

45013

112808

6.79

53.30

39.90

More information:

Cholesterol is a fat-like substance (lipid) that is present in cell membranes and is a precursor of bile acids and steroid hormones. Normally cholesterol travels in the blood in distinct particles containing both lipid and proteins (lipoproteins). In modern times, non-HDL cholesterol (non-HDL-C) has become a commonly used marker for a blood lipid pattern associated with increased risk of heart disease.

Dyslipidemia is a primary and major risk factor for CAD and may even be a prerequisite for CAD, occurring before other major risk factors come into play. Epidemiologic data also suggest that hypercholes­terolemia and perhaps coronary atherosclerosis itself are risk factors for ischemic stroke. Medical professionals typically test cholesterol levels through medical check-ups and in order to evaluate total cholesterol, triglycerides, and HDL-C.

Atherosclerosis is the most well-known and the fundamental reason for cardiovascular diseases. Atherosclerosis is a condition where the arteries become narrowed and hardened due to an excessive build-up of plaque in the artery wall, which is formed by accumulation of lipids, which leads to CAD. It is generally mediated by a complex interaction between lipoproteins, white blood cells and the normal components of the arterial wall.

(Reference range: The National Cholesterol Education Program (NCEP) Adult Treatment Panel III report . Cholesterol Total:Desirable< 200 mg/dL, Borderline high: 200-239 mg/dL, High: 240 mg/dL, Triglyceride: Normal < 150 mg/dL, Borderline high: 150-199 mg/dL, High: 200-499 mg/dL, Very high: 500 mg/dL, HDL: Major risk factor < 40 mg/dL, Negative risk factor > 60 mg/dL, LDL: Optimal: 100-129 mg/dL, Borderline high: 130-159 mg/dL, High: 160-189 mg/dL, Very high: 190)

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